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Exemestane

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Country of Origin︰China
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Product Description

CAS 107868-30-4  (email: hrycgl001@chembj.com)
Exemestane

Product name: Exemestane
Alias: Aromasin ; Exemestan;Exemestane,Exemestane Aromasin
Product Category: Pharmaceutical raw materials and intermediates
Assay: 98%min
CAS Registry Number:107868-30-4
Molecular formula: C20H24O2

Molecular weight:296.40
Appearance: White or Almost White Crystalline Powder
Grade : Pharmaceutical Grade
Storage: Shading, confined preservation
Usage: Developed to help fight breast cancer, Aromasin is one of the most powerful estrogen suppressing compounds
Other drugs in same class: Anastrozole,Letrozole,Tamoxifen citrate,Exemestane
 
Product Description:

Exemestane is an oral steroidal aromatase inhibitor that is used in ER-positive breast cancer in addition to surgery and/or radiation in post-menopausal women.

The main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced via the conversion of androgens into estrogen by the aromatase enzyme in the peripheral tissues (i.e. adipose tissue like that of the breast) and a number of sites in the brain. Estrogen is produced locally via the actions of the aromatase enzyme in these peripheral tissues where it acts locally. Any circulating estrogen in post-menopausal women as well as men is the result of estrogen escaping local metabolism and entering the circulatory system.

Applications:

Exemestane is an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate . It acts as a false substrate for the aromatase enzyme, and is processed to an intermediate that binds irreversibly to the active site of the enzyme causing its inactivation, an effect also known as "suicide inhibition." By being structurally similar to enzyme targets, Exemestane permanently binds to the enzymes, preventing them from converting androgen into estrogen.
Competitive Advantage:

1. Our company is a professional production leading factory in China in pharmaceutical area of many years. Delivery areas of our products:US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.

Payment method: T/T, Western union, Moneygram
2. Discreet package .The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration .
3. Top quality. High quality guaranteed, once any problem is found, the package would be reshipped for you .
4. Security Shipping:Shipping by express (FedEx,UPS,DHL,EMS), by air.The most professional forwarder would be recommanded for you.
5. We have stock, so we can delivery quickly at the very day when receive the payment.
6. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
7. A discount would be given when you make a large order.
 
 
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Payment Terms︰TT / LC / DP / DA
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