CAS 128446-35-5 Hydroxypropyl-beta-cyclodextrin
Product Name: Hydroxypropyl-beta-cyclodextrin
Appearance: White powder
Features and use: introducing hydroxypropyl broke the intramolecular hydrogen bond with β - cyclodextrin, while maintaining the cyclodextrin cavity at the same time to overcome the main disadvantages of β - cyclodextrin with poor solubility in water. Is the best studied, one of the most widely used cyclodextrin derivatives. Mainly used in food, medicine, cosmetics industry.
1, in the field of food, spices, can improve the stability of trophic molecules and long-term, bad smell and taste can cover up or correction of food nutrition molecules, to improve the production process and product quality. This product is very good in water solubility, degree of substitution of 4 and above can be arbitrary proportion and water miscible, can also be dissolved in 50% ethanol and methanol.
2, in the cosmetics raw materials used as stabilizers, emulsifiers, deodorizing agent, can reduce the stimulation of organic molecules in cosmetics to skin and mucous membrane organization, enhance the stability of active ingredients, to prevent the volatilization, oxidation of nutrients. It has relatively certain hygroscopic.
3, in the pharmaceutical industry, due to the relative surface activity and hemolytic activity is relatively low and no stimulation to muscle, so it is a kind of ideal injection solubilizing agent and pharmaceutical excipient. Can increase the dissolution rate of water-soluble, increase the bioavailability of drugs, drug stability, increase the efficacy of the drug or dose reduction, can adjust or control the drug release rate, reduce side effects of drugs. Can be used in oral medicine, injection, mucosal drug delivery system (including the nasal, rectal, cornea and so on), transdermal drug delivery system, lipophilic drug targeting carrier, agent and stabilizer protection can also be used as a protein.